Fatal hemorrhage in irradiated esophageal cancer patients

Kenji Nemoto, Yoshihiro Takai, Yoshihiro Ogawa, Yoshihisa Kakuto, Hisanori Ariga, Haruo Matsushita, Hitoshi Wada, Shogo Yamada

研究成果: Article査読

15 被引用数 (Scopus)

抄録

Between 1980 and 1994, 423 patients with esophageal cancer were given curative radiation therapy. Of these patients, 31 died of massive hemorrhage and were used as the subjects of analysis in this study. The incidence of massive hemorrhage in all patients was 7% (31/423). In the 31 patients who died of massive hemorrhage, 27 had local tumors and two had no tumors at hemorrhage (two unknown cases). The mean time interval from the start of radiation to hemorrhage was 9.2 months. In 9 autopsy cases the origin of hemorrhage was a tear of the aorta in 5 cases, necrotic local tumor in 3 cases and esophageal ulcer in 1 case. The positive risk factors for this complication seemed to be excess total dose, infection, metallic stent, and tracheoesophageal fistula. Chest pain or sentinel hemorrhage proceeding to massive hemorrhage was observed in about half of the patients.

本文言語English
ページ(範囲)259-262
ページ数4
ジャーナルActa Oncologica
37
3
DOI
出版ステータスPublished - 1998

ASJC Scopus subject areas

  • 血液学
  • 腫瘍学
  • 放射線学、核医学およびイメージング

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