Fabrication of pure nanodrugs of podophyllotoxin dimer and their anticancer activity

Yoshikazu Ikuta, Yoshitaka Koseki, Tatsuya Murakami, Minoru Ueda, Hidetoshi Oikawa, Hitoshi Kasai

研究成果: Article査読

11 被引用数 (Scopus)

抄録

Drug nanoparticles of water-insoluble bioactive compounds are potentially applicable in next-generation drug delivery systems (DDSs). As an example of such nanoparticles, the dimeric podophyllotoxin (PPT) was synthesized, and PPT nanoparticles were fabricated by the reprecipitation method. It was found that these nanoparticles show much higher cytotoxity for cancer cells as compared to etoposide, which is an analog of PPT.

本文言語English
ページ(範囲)900-901
ページ数2
ジャーナルChemistry Letters
42
8
DOI
出版ステータスPublished - 2013

ASJC Scopus subject areas

  • 化学 (全般)

フィンガープリント

「Fabrication of pure nanodrugs of podophyllotoxin dimer and their anticancer activity」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル