ERK MAP kinase in G1 cell cycle progression and cancer

Satoru Torii, Takuya Yamamoto, Yoshiki Tsuchiya, Eisuke Nishida

    研究成果: Review article査読

    194 被引用数 (Scopus)

    抄録

    The extracellular-signal-regulated kinase (ERK) mitogen-activated protein (MAP) kinase signaling pathway plays an important role in various cellular responses, including cell proliferation, cell differentiation and cell survival. Recent studies have identified a number of Ras/ERK signaling-related proteins, such as scaffold proteins and inhibitors. These proteins modulate ERK signaling and thereby could give variations in ERK signaling outputs that regulate cell fate decisions. Here we focus on the role of ERK signaling in cell cycle progression from G0/G1 to S phase and cancer.

    本文言語English
    ページ(範囲)697-702
    ページ数6
    ジャーナルCancer science
    97
    8
    DOI
    出版ステータスPublished - 2006 8月 1

    ASJC Scopus subject areas

    • 腫瘍学
    • 癌研究

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