Enhancement of high-intensity focused ultrasound heating by short-pulse generated cavitation

Shin Yoshizawa, Ryo Takagi, Shin Ichiro Umemura

研究成果: Review article査読

18 被引用数 (Scopus)

抄録

A target tissue can be thermally coagulated in high-intensity focused ultrasound (HIFU) treatment noninvasively. HIFU thermal treatments have been clinically applied to various solid tumors. One of the problems in HIFU treatments is a long treatment time. Acoustically driven microbubbles can accelerate the ultrasonic heating, resulting in the significant reduction of the treatment time. In this paper, a method named "trigger HIFU exposure" which employs cavitation microbubbles is introduced and its results are reviewed. A trigger HIFU sequence consists of high-intensity short pulses followed by moderate-intensity long bursts. Cavitation bubbles induced in a multiple focal regions by rapidly scanning the focus of high-intensity pulses enhanced the temperature increase significantly and produced a large coagulation region with high efficiency.

本文言語English
論文番号288
ジャーナルApplied Sciences (Switzerland)
7
3
DOI
出版ステータスPublished - 2017

ASJC Scopus subject areas

  • 材料科学(全般)
  • 器械工学
  • 工学(全般)
  • プロセス化学およびプロセス工学
  • コンピュータ サイエンスの応用
  • 流体および伝熱

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