TY - JOUR
T1 - Endfolium sclerosis in temporal lobe epilepsy diagnosed preoperatively by 3-tesla magnetic resonance imaging
T2 - Case report
AU - Iwasaki, Masaki
AU - Nakasato, Nobukazu
AU - Suzuki, Hiroyoshi
AU - Tominaga, Teiji
PY - 2009/6
Y1 - 2009/6
N2 - A 34-year-old man presented with intractable temporal lobe epilepsy. Three-tesla magnetic resonance imaging revealed increased T2 signal intensity and volume loss limited to the CA4 region of the right hippocampus. A right anterior temporal lobectomy and amygdalohippocampectomy were performed. Histological examination of the hippocampus disclosed severe neuron loss limited to the CA4 region, consistent with the preoperative imaging, which is a pattern known as endfolium sclerosis. Close inspection of the internal hippocampal anatomy with high-field MR imaging is useful in patients with temporal lobe epilepsy, because endfolium sclerosis may be associated with less chance of seizure freedom after temporal lobectomy.
AB - A 34-year-old man presented with intractable temporal lobe epilepsy. Three-tesla magnetic resonance imaging revealed increased T2 signal intensity and volume loss limited to the CA4 region of the right hippocampus. A right anterior temporal lobectomy and amygdalohippocampectomy were performed. Histological examination of the hippocampus disclosed severe neuron loss limited to the CA4 region, consistent with the preoperative imaging, which is a pattern known as endfolium sclerosis. Close inspection of the internal hippocampal anatomy with high-field MR imaging is useful in patients with temporal lobe epilepsy, because endfolium sclerosis may be associated with less chance of seizure freedom after temporal lobectomy.
KW - Endfolium sclerosis
KW - Epilepsy surgery
KW - Hippocampal sclerosis
KW - Magnetic resonance imaging
KW - Temporal lobe epilepsy
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UR - http://www.scopus.com/inward/citedby.url?scp=67650797317&partnerID=8YFLogxK
U2 - 10.3171/2008.11.JNS081109
DO - 10.3171/2008.11.JNS081109
M3 - Article
C2 - 19326971
AN - SCOPUS:67650797317
VL - 110
SP - 1124
EP - 1126
JO - Journal of Neurosurgery
JF - Journal of Neurosurgery
SN - 0022-3085
IS - 6
ER -