Enantioselective total synthesis of idesolide via NaHCO3- promoted dimerization

Tomohiro Nagasawa, Naoyuki Shimada, Munefumi Torihata, Shigefumi Kuwahara

研究成果: Article査読

17 被引用数 (Scopus)

抄録

The enantioselective total synthesis of idesolide has been accomplished in 20% overall yield from a known allylic alcohol by a nine-step sequence involving the Sharpless asymmetric epoxidation as the source of chirality and an efficient NaHCO3-promoted dimerization of the monomeric form of idesolide as the key transformation.

本文言語English
ページ(範囲)4965-4969
ページ数5
ジャーナルTetrahedron
66
27-28
DOI
出版ステータスPublished - 2010 7 3

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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