Enantioselective total synthesis of antiangeogenic pentaketide dimers, epoxyquinols A and B, through an asymmetric aldol approach to their common monomeric precursor

Shigefumi Kuwahara, Sunao Imada

研究成果: Article査読

26 被引用数 (Scopus)

抄録

A new enantioselective total synthesis of epoxyquinols A and B possessing unique pentaketide dimeric structures and potent antiangeogenic activity was achieved by oxidative dimerization of a monomeric pentaketide precursor obtained by the Evans asymmetric aldol reaction and a series of operationally simple transformations.

本文言語English
ページ(範囲)547-549
ページ数3
ジャーナルTetrahedron Letters
46
4
DOI
出版ステータスPublished - 2005 1 24

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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