@article{3c5088d26f87443ca0077ee4406ec45a,
title = "Enantioselective synthesis of rumphellaone A via epoxy nitrile cyclization",
abstract = "The first enantioselective synthesis of rumphellaone A, a cytotoxic 4,5-seco-caryophyllane derivative incorporating a γ-lactone ring as its structural feature, has been achieved by using base-induced intramolecular cyclization of an epoxy nitrile intermediate to install its cyclobutane skeleton as well as three contiguous stereocenters as the key transformation.",
keywords = "Caryophyllane, Cytotoxic, Epoxy nitrile cyclization, Rumphellaone A",
author = "Takafumi Hirokawa and Tomohiro Nagasawa and Shigefumi Kuwahara",
note = "Funding Information: This work was supported, in part, by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan (No. 22380064 ). ",
year = "2012",
month = feb,
day = "8",
doi = "10.1016/j.tetlet.2011.11.145",
language = "English",
volume = "53",
pages = "705--706",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "6",
}