Electrochemical gene-function analysis for single cells with addressable microelectrode/microwell arrays

Zhenyu Lin; Yasufumi Takahashi; Tatsuya Murata; Michiaki Takeda; Kosuke Ino; Hitoshi Shiku; Tomokazu Matsue

doi:10.1002/anie.200805743

Electrochemical gene-function analysis for single cells with addressable microelectrode/microwell arrays

Zhenyu Lin, Yasufumi Takahashi, Tatsuya Murata, Michiaki Takeda, Kosuke Ino, Hitoshi Shiku, Tomokazu Matsue

研究成果: Article › 査読

55 被引用数 (Scopus)

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(Graph Presented) To each his own: An addressable electrochemical device consisting of orthogonally arranged rows and columns of electrodes has been constructed to monitor protein expression in genetically engineered cells at the single-cell level. The response based on redox cycling reflected the different expression levels of the enzyme from individual HeLa cells transfected with a plasmid vector including secreted alkaline phosphatase.

本文言語	English
ページ（範囲）	2044-2046
ページ数	3
ジャーナル	Angewandte Chemie - International Edition
巻	48
号	11
DOI	https://doi.org/10.1002/anie.200805743
出版ステータス	Published - 2009 3月 2

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化学 (全般)

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10.1002/anie.200805743

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AU - Ino, Kosuke

AU - Shiku, Hitoshi

AU - Matsue, Tomokazu

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KW - Electrochemistry

KW - High-throughput screening

KW - Microelectrodes

KW - Single-cell analysis

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Electrochemical gene-function analysis for single cells with addressable microelectrode/microwell arrays

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