TY - JOUR
T1 - Efficient thermal lens nanoparticle detection in a flow-focusing microfluidic device
AU - Yamaoka, Satomi
AU - Kataoka, Yui
AU - Kazama, Yuto
AU - Fujii, Yusaku
AU - Hibara, Akihide
N1 - Funding Information:
A part of this study was supported by JSPS KAKENHI Grant number 15H03825 , by JSPS-RFBR Japan-Russia Research Cooperative Program, and by the Food Nanotechnology Project of the Ministry of Agriculture, Forestry, and Fisheries of Japan.
Publisher Copyright:
© 2016 Elsevier B.V. All rights reserved.
Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 2016/6/2
Y1 - 2016/6/2
N2 - A flow-focusing microfluidic device was fabricated for thermal lens nanoparticle detection. In this device, sample flow was first sandwiched by lateral z-axis sheath flows, and then by horizontal xy-plane sheath flows. The three-dimensional flow focus was visualized using an aqueous dye solution. Subsequently, 500-nm-sized red polystyrene particles were individually detected by the thermal lens detection method. When 1 μL of sample solution containing 300 particles/μL was passed through the thermal lens detection point, 255 ± 20 peaks corresponding to particles were observed.
AB - A flow-focusing microfluidic device was fabricated for thermal lens nanoparticle detection. In this device, sample flow was first sandwiched by lateral z-axis sheath flows, and then by horizontal xy-plane sheath flows. The three-dimensional flow focus was visualized using an aqueous dye solution. Subsequently, 500-nm-sized red polystyrene particles were individually detected by the thermal lens detection method. When 1 μL of sample solution containing 300 particles/μL was passed through the thermal lens detection point, 255 ± 20 peaks corresponding to particles were observed.
KW - Flow focus
KW - Microfluidics
KW - Nanoparticle
KW - Polydimethylsiloxane
KW - Thermal lens
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U2 - 10.1016/j.snb.2016.01.072
DO - 10.1016/j.snb.2016.01.072
M3 - Article
AN - SCOPUS:84956702966
VL - 228
SP - 581
EP - 586
JO - Sensors and Actuators B: Chemical
JF - Sensors and Actuators B: Chemical
SN - 0925-4005
ER -