Efficient synthesis of core 2 class glycosyl amino acids by one-pot glycosylation approach

Hiroshi Tanaka, Masaatsu Adachi, Takashi Takahashi

研究成果: Article査読

48 被引用数 (Scopus)

抄録

We describe the one-pot synthesis of core 2 class branched oligosaccharides initiated by chemo-selective glycosylation of silyl ether. Glycosylation of 6-O-silyl-4-benzyl-2-azido-thiogalactoside with glycosyl fluoride provided selectively 6-glycosylated thioglycoside without both O-glycosylation at the 3 position and S-glycosylation. Subsequent coupling of galactosyl fluoride and amino acids afforded the protected branched oligosaccharides in good yields.

本文言語English
ページ(範囲)1433-1436
ページ数4
ジャーナルTetrahedron Letters
45
7
DOI
出版ステータスPublished - 2004 2月 9
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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