Effects of rose bengal on cavitation generation in gel phantom investigated using high-speed camera

Jun Yasuda, Takuya Miyashita, Shin Yoshizawa, Shin Ichiro Umemura

研究成果: Article査読

10 被引用数 (Scopus)

抄録

Acoustic cavitation bubbles are microbubbles generated by the highly negative pressure of ultrasound. They are known to enhance the thermal bioeffect of high-intensity focused ultrasound (HIFU) treatment. Other than the use of the thermal bioeffect, sonodynamic treatment using the sonochemical bioeffect of ultrasound has been proposed. In sonodynamic treatment, a sonosensitizer is activated through the collapse of cavitation bubbles to induce a therapeutic effect sonochemically. Rose Bengal (RB) has the potential to be such a sonosensitizer. Highly efficient as well as controlled generation of cavitation bubbles is crucial for realizing effective as well as safe sonodynamic treatment. The effect of RB on cavitation generation was investigated to achieve such controlled generation. The amount and behavior of the cavitation bubbles generated by a triggered HIFU sequence in the presence of RB were observed using a high-speed camera for estimating the effect of RB. Results showed that RB increased the area of the cavitation cloud and the lifetime of sustained cavitation bubbles.

本文言語English
論文番号07KF20
ジャーナルJapanese journal of applied physics
53
7 SPEC. ISSUE
DOI
出版ステータスPublished - 2014 7

ASJC Scopus subject areas

  • 工学(全般)
  • 物理学および天文学(全般)

フィンガープリント

「Effects of rose bengal on cavitation generation in gel phantom investigated using high-speed camera」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル