Effects of Qing Fei Tang (TJ-90) on aspiration pneumonia in mice

K. Iwasaki, Q. Wang, N. Satoh, S. Yoshida, T. Akaike, K. Sekizawa, H. Maeda, H. Sasaki

研究成果: Article査読

8 被引用数 (Scopus)

抄録

The effects of Qing Fei Tang (Sei-hai To in Japanese), a Chinese traditional medical mixture, on aspiration pneumonia were studied using mice inoculated with both Streptococcus pneumoniae and gastric juice as aspiration pncumoniae models. Daily (4 weeks) oral usage of Qing Fei Tang before inoculation reduced remarkably the mortality rate of mice. In this aspiration pneumonia model, xanthine oxidase (XO) activity in the lung tissues was elevated, but this elevation was remarkably decreased by use of Qing Fei Tang. These results suggest that Qing Fei Tang pretreatment can reduce oxygen radical production in inflammed lungs and may reduce the mortality for aspiration pneumonia.

本文言語English
ページ(範囲)95-101
ページ数7
ジャーナルPhytomedicine
6
2
DOI
出版ステータスPublished - 1999 5
外部発表はい

ASJC Scopus subject areas

  • 分子医療
  • 薬理学
  • 薬科学
  • 創薬
  • 補完代替医療

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