Motion of a subject during PET scanning is a significant source of errors in myocardial PET studies. We have developed a motion-correction system based on a rigid body model for thorax PET studies. The present study was intended to evaluate this system in the myocardial blood flow (MBF) study using 15O-labeled water on a normal volunteer. We artificially shifted the bed of the PET scanner horizontally by 30 mm to simulate the subject's repositioning, in addition to a natural movement in the order of 10 mm. The shift was monitored successfully using the system developed. The motion correction provided values of myocardial blood flow with a better reproducibility as compared with those without the motion correction.
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