Effects of capsaicin treatment on nociception and structure of trigeminal nerve fibers in adult rats

Akiko Kato, Megumi Nakamura, Seishi Echigo, Yasuyuki Sasano

研究成果: Chapter

抄録

Systemic capsaicin treatment has been used in animal research to eliminate sensory nerve function, but little is known about physiological and morphological effects. We investigated the time-dependent changes in nociception and the ultrastructure of sensory nerve fibers after administration of capsaicin in rats. Capsaicin treatment caused transient loss of sensitivity, but transmission electron microscopy showed no structural changes of trigeminal nerve fibers in capsaicin- treated rats as well as controls. These results suggest that the structural damage to sensory nerve fibers may not be a cause of the reduction of sensitivity.

本文言語English
ホスト出版物のタイトルInterface Oral Health Science 2011
出版社Springer Japan
ページ140-142
ページ数3
ISBN(電子版)9784431540700
ISBN(印刷版)9784431540694
DOI
出版ステータスPublished - 2012 1月 1

ASJC Scopus subject areas

  • 歯科学(全般)

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