Effect of periodic phase shift on acoustic cavitation induction with second-harmonic superimposition

Ken Ichi Kawabata, Shin Ichiro Umemura

研究成果: Article査読

16 被引用数 (Scopus)

抄録

Second-harmonic superimposition (SHS) is an ultrasound exposure method for efficiently inducing cavitation both in vitro and in vivo. Its efficiency is dependent on SH phase relative to the fundamental. In this study, we investigated the effect of periodical shifting of the relative phase on the cavitation induction by using SHS. In an aqueous solution, SH phase shifting with a shift pitch not larger than 0.5 π and a shift interval time not shorter than 30 ms was found to be as effective in inducing cavitation as the SH phase is fixed to the optimum phase. This result is important for the application of SHS to in vivo treatment in which it is difficult to maintain the relative phase in a target tissue constant because of movements and biophysical changes.

本文言語English
ページ(範囲)3246-3250
ページ数5
ジャーナルJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
42
5 B
出版ステータスPublished - 2003 5 1

ASJC Scopus subject areas

  • 工学(全般)
  • 物理学および天文学(全般)

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