Effect of Intracoronary Thrombectomy on 30-Day Mortality in Patients With Acute Myocardial Infarction

Daisaku Nakatani, Hiroshi Sato, Yasuhiko Sakata, Hiroya Mizuno, Masahiko Shimizu, Shinichiro Suna, Shinsuke Nanto, Atsushi Hirayama, Hiroshi Ito, Kenshi Fujii, Masatsugu Hori

研究成果: Article査読

12 被引用数 (Scopus)

抄録

Insertion of intracoronary thrombectomy (ICT) devices, as a precedent to percutaneous coronary intervention (PCI), theoretically could have a beneficial effect on the outcome in patients with acute myocardial infarction. To examine whether ICT was associated with a lower 30-day mortality rate in patients with acute myocardial infarction, we studied 3,913 patients who underwent PCI within 24 hours after onset. A total of 990 patients (25.3%) were treated with ICT before PCI. The 30-day mortality rate was lower in the patients receiving ICT than in those without (3.7% vs 6.2%, p = 0.004), but this beneficial effect disappeared after adjustment for baseline characteristics (hazard ratio [HR] 0.658, p = 0.166). We also divided the patients into tertiles according to the Thrombolysis In Myocardial Infarction (TIMI) risk score. After adjustment for baseline characteristics, ICT was associated with a lower 30-day mortality rate in patients from the highest TIMI risk score tertile (HR 0.407, p = 0.029), but not in patients from the lower 2 tertiles. ICT was also an independent predictor of a lower 30-day mortality risk in patients aged ≥70 years (HR 0.239, p = 0.007), patients with diabetes mellitus (HR 0.275, p = 0.039), and those with stent implantation (HR 0.437, p = 0.034). In conclusion, in selected patients with high TIMI risk scores, an age ≥70 years, diabetes mellitus, or stenting, ICT is associated with a lower 30-day mortality rate.

本文言語English
ページ(範囲)1212-1217
ページ数6
ジャーナルAmerican Journal of Cardiology
100
8
DOI
出版ステータスPublished - 2007 10 15
外部発表はい

ASJC Scopus subject areas

  • 循環器および心血管医学

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