Effect of intracoronary thrombectomy on 30-day mortality in non-diabetic patients with acute hyperglycemia after acute myocardial infarction

Masaya Usami, Yasuhiko Sakata, Daisaku Nakatani, Masahiko Shimizu, Shinichiro Suna, Sen Matsumoto, Masatsugu Hori, Hiroshi Sato

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Background: There is limited evidence about useful therapeutic interventions for patients with acute hyperglycemia (AH) after acute myocardial infarction (AMI). Methods: We studied 2433 consecutive non-diabetic AMI patients who underwent percutaneous coronary intervention (PCI) within 24 h after the onset. Patients were divided into two groups according to the presence or absence of AH (admission serum glucose level ≥11.1 mmol/l). We assessed the association between intracoronary thrombectomy and the clinical outcome in AMI patients with AH. Results: Patients with AH had more risk factors than those without AH. The 30-day mortality rate of patients with AH was significantly higher than that of those without (11.7% vs 1.7%, p < 0.001). Among patients with AH, the 30-day mortality rate was significantly lower for those with intracoronary thrombectomy than those without it (4.9% vs 17.2%, p = 0.004). Among patients without AH, however, the 30-day mortality rate was similar between those with and without intracoronary thrombectomy (1.5% vs 1.9%, p = NS). Multivariate analysis showed that intracoronary thrombectomy was associated with an improved 30-day mortality rate for patients with AH (hazard ratio: HR 0.184, 95% CI 0.057-0.598, p = 0.005). Conclusions: In AMI patients with AH, intracoronary thrombectomy prior to PCI might improve the 30-day mortality rate.

本文言語English
ページ(範囲)429-436
ページ数8
ジャーナルJournal of cardiology
53
3
DOI
出版ステータスPublished - 2009 6
外部発表はい

ASJC Scopus subject areas

  • 循環器および心血管医学

フィンガープリント

「Effect of intracoronary thrombectomy on 30-day mortality in non-diabetic patients with acute hyperglycemia after acute myocardial infarction」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル