Effect of difference in shear modulus of biological tissue on heat source distribution of high-intensity focused ultrasound estimated by acoustic radiation force imaging

Hiroki Yabata, Shinichiro Umemura, Shin Yoshizawa

研究成果: Article査読

抄録

High-intensity focused ultrasound (HIFU) is a novel noninvasive cancer treatment that is expected to be a potential alternative to conventional therapies. In the treatment, the accurate prediction of the ultrasonic heat source prior to therapeutic exposure is important for safety and efficacy. Acoustic radiation force imaging using a short HIFU burst has been proposed as a method for this prediction from the distribution of the tissue displacement. In this study, the effect of the difference in shear modulus on the estimation of the HIFU heat source was experimentally investigated by applying the imaging method to different biological tissues: chicken breast and chicken liver tissues. The result suggested that HIFU radiation force imaging has the potential to determine the HIFU power for appropriate treatment quantitatively from the displacement, even in different tissues with different shear moduli.

本文言語English
論文番号SDDE23
ジャーナルJapanese journal of applied physics
60
DOI
出版ステータスPublished - 2021 7

ASJC Scopus subject areas

  • 工学(全般)
  • 物理学および天文学(全般)

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