Effect of dietary seal and fish oils on lipid metabolism in hamsters

H. Yoshida, I. Ikeda, M. Tomooka, M. Mawatari, K. Imaizumi, A. Seto, H. Tsuji

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Eicosapentaenoic and docosahexaenoic acids were distributed mainly in the sn-1 and 3 positions of seal oil triacylglycerols and in the sn-2 position of fish oil triacylglycerols. Seal oil-rich or fish oil-rich fats having constant polyunsaturated (PUFAs)/monounsaturated/saturated fatty acids and n-6/n-3 PUFAs ratios were fed to hamsters for 3 weeks. The control fat contained linoleic acid as the sole PUFA. The concentration of triacylglycerols in the liver was significantly lower in the fish oil group than in the control group. Phospholipid concentration in serum was lower and that in the liver was higher in the seal oil group compared with the fish oil group. The activities of fatty acid synthase (FAS), glucose-6-phosphate dehydrogenase (G6PDH), and the malic enzyme were significantly lower in both the fish and seal oil groups than in the control group. Dietary seal oil more effectively reduced arachidonic acid content in liver phosphatidylcholine and phosphatidylethanolamine and serum phosphatidylcholine than fish oil. These results showed that different intramolecular distribution of n-3 PUFAs influenced glycerolipid metabolism and arachidonic acid content in serum and liver phospholipids of hamsters.

本文言語English
ページ(範囲)242-247
ページ数6
ジャーナルJournal of nutritional science and vitaminology
47
3
DOI
出版ステータスPublished - 2001
外部発表はい

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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