Effect of CpG ODN on monocytic myeloid derived suppressor cells

Hidekazu Shirota, Dennis M. Klinman

研究成果: Article査読

14 被引用数 (Scopus)

抄録

CpG oligonucleotides stimulate via TLR9 and enhance anti-tumor immunity, an effect attributed to the activation of NK and CD8+ T cells. Our recent work demonstrates that CpG ODN also induce monocytic myeloid-derived suppressor cells to mature into M1 macrophages, further aiding tumor elimination. This provides insight into the mechanism through which CpG promote tumor regression.

本文言語English
ページ(範囲)780-782
ページ数3
ジャーナルOncoImmunology
1
5
DOI
出版ステータスPublished - 2012
外部発表はい

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

フィンガープリント 「Effect of CpG ODN on monocytic myeloid derived suppressor cells」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル