Early-stage primary malignant melanoma of the esophagus detected simultaneously with esophageal squamous cell carcinoma

Makoto Hikage, Takashi Kamei, Fumiyoshi Fujishima, Goh Miyata, Ko Onodera, Hirofumi Ichikawa, Toru Hoshida, Hiroshi Kikuchi, Toru Nakano, Jin Teshima, Motoo Fujita, Hironobu Sasano, Susumu Satomi

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Primary malignant melanoma of the esophagus is a rare disease. The majority of patients are diagnosed at an advanced stage, and only a few are detected at an early stage. We herein describe a case of early-stage primary malignant melanoma of the esophagus that was detected simultaneously with early-stage primary esophageal squamous cell carcinoma. Both tumors were detected during esophagogastroduodenoscopy for heartburn. The malignant melanoma tumor was a nevus-like flat-type lesion in the upper thoracic esophagus, and the squamous cell carcinoma was a slightly depressed lesion in the abdominal esophagus. The tumor was resected by thoracoscopic esophagectomy. Histologically, the invasion of both tumors was limited to the mucosal layer, and no lymph node metastasis was detected. Immunohistochemically, the malignant melanoma cells were strongly positive for HMB-45, melan-A, and S-100 protein. The patient has survived without recurrence for 17 months after the operation.

本文言語English
ページ(範囲)33-38
ページ数6
ジャーナルEsophagus
9
1
DOI
出版ステータスPublished - 2012 3 1

ASJC Scopus subject areas

  • 消化器病学

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