Dynamic assembly/disassembly processes of photoresponsive DNA origami nanostructures directly visualized on a lipid membrane surface

Yuki Suzuki, Masayuki Endo, Yangyang Yang, Hiroshi Sugiyama

研究成果: Article

72 引用 (Scopus)

抜粋

Here, we report the direct visualization of the assembly/disassembly processes of photoresponsive DNA origami nanostructures which can be placed on a lipid bilayer surface. The observation relies on controlled interactions between the bilayer components and cholesterol moieties introduced to the hexagonal origami structures, one of whose outer edges carries Azo-ODNs. The bilayer-placed hexagonal dimer was disassembled into monomer units by UV irradiation, and reversibly assembled again during visible light irradiation. These dynamic processes were directly monitored with high-speed atomic force microscopy. The successful application of our approach should facilitate studies of interactive and functional behaviors of various DNA nanostructures.

元の言語English
ページ(範囲)1714-1717
ページ数4
ジャーナルJournal of the American Chemical Society
136
発行部数5
DOI
出版物ステータスPublished - 2014 2 5

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

フィンガープリント Dynamic assembly/disassembly processes of photoresponsive DNA origami nanostructures directly visualized on a lipid membrane surface' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用