Duodenal but not gastric transection disturbs motility of the sphincter of Oddi in the dog

Chikashi Shibata, Iwao Sasaki, Hiroo Naito, Noriya Ohtani, Shoichi Sato, Hideo Ise, Seiki Matsuno

研究成果: Article査読

10 被引用数 (Scopus)

抄録

The aim of the present study was to elucidate the effect of gastric and duodenal transection on biliary manometry in anesthetized dogs. The basal biliary pressure and increase in pressure during saline perfusion at rates of 1.0 and 1.5 ml/min were studied in intact controls, during infusion of cholecystokinin (CCK) alone, and after gastric and duodenal transection. CCK dose-dependently lowered the basal pressure and the increase in pressure during perfusion. Gastric transection 1.5 cm proximal to the pylorus did not affect these parameters. In contrast, duodenal transection 1.0 cm distal to the pylorus significantly increased these parameters compared to all other groups. These observations suggest that the proximal duodenal transection, as performed during conventional distal gastrectomy, may contribute to the pathogenesis of postgastrectomy gallstone formation by altering motor function of the sphincter of Oddi.

本文言語English
ページ(範囲)191-194
ページ数4
ジャーナルWorld Journal of Surgery
21
2
DOI
出版ステータスPublished - 1997

ASJC Scopus subject areas

  • 外科

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