Carbohydrates bind proteins multivalently to enhance the affinity between them. This multivalent interaction called a glycoside cluster effect has received much attention from not only carbohydrate chemists but also medicinal and natural product chemists. Herein the recent progress of the drug discovery research using a cluster effect is reviewed.
|ジャーナル||Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry|
|出版ステータス||Published - 2015 4|
ASJC Scopus subject areas
- Organic Chemistry