@article{5290b183a24c4ca3a1218eb46eb8f890,
title = "Double Functionalization of Styrenes by Cu-Mediated Assisted Tandem Catalysis",
abstract = " The double functionalization of styrenes through Cu-mediated assisted tandem catalysis was developed. The reaction was initiated by Cu-catalyzed aziridination and the subsequent nucleophilic ring-opening, which was triggered by the addition of (NH 4 ) 2 S 2 O 8 as an oxidant of Cu-catalyst to form a variety of C–C and C–X bonds. The expansion to three contiguous catalytic cycles led to the synthesis of functionalized indolines by one-pot operation. ",
keywords = "Cu-catalysis, Double functionalization, Indolines, Spirocycle, Tandem catalysis",
author = "Daichi Kawauchi and Hirofumi Ueda and Hidetoshi Tokuyama",
note = "Funding Information: This work was supported by Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)) from AMED under Grant Number JP18am0101100, JSPS KAK-ENHI Grant Numbers JP18H04231 in Precisely Designed Catalysts with Customized Scaffolding and JP18H04642 in Hybrid Catalysis, a Grant-in aid for Scientific Research (B) (18H02549) and (C) (17K08204). Publisher Copyright: {\textcopyright} 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2019",
month = mar,
day = "14",
doi = "10.1002/ejoc.201900088",
language = "English",
volume = "2019",
pages = "2056--2060",
journal = "Annalen der Pharmacie",
issn = "0075-4617",
publisher = "Wiley-VCH Verlag",
number = "10",
}