Double bond isomerization/enantioselective aza-petasis-ferrier rearrangement sequence as an efficient entry to anti- and enantioenriched β-Amino Aldehydes

Masahiro Terada, Yasunori Toda

研究成果: Article査読

125 被引用数 (Scopus)

抄録

Highly anti- and enantioselective synthesis of .-amino aldehydes having an aliphatic substituent at the .-position was accomplished by a combination of two catalytic reactions, that is, an initial Ni(II) complex-catalyzed isomerization of a double bond followed by a chiral phosphoric acid catalyzed aza-Petasis-Ferrier rearrangement, using hemiaminal allyl ethers as the initial substrate. The chiral phosphoric acid also functioned as an efficient resolving catalyst of racemic hemiaminal vinyl ethers.

本文言語English
ページ(範囲)6354-6355
ページ数2
ジャーナルJournal of the American Chemical Society
131
18
DOI
出版ステータスPublished - 2009 5 13

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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