Dorsolateral prefrontal cortex activity during a brain training game predicts cognitive improvements after four weeks’ brain training game intervention: Evidence from a randomized controlled trial

Rui Nouchi, Natasha Yuriko Dos Santos Kawata, Toshiki Saito, Robin Maximilian Himmelmeier, Ryo Nakamura, Haruka Nouchi, Ryuta Kawashima

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Background: Recent studies have demonstrated that brain activities using NIRS (near-infrared spectroscopy) at baseline during cognitive tasks (e.g., N-back task) can predict the cognitive benefits of a cognitive training. In this study, we investigated whether brain activities during brain training game (BT) at baseline would predict benefits to cognitive functions after the intervention period. Methods: In a four-week double-blinded randomized control trial (RCT) 72 young adults were randomly assigned to one of the two groups: participants in the BT group played specific game, called the Brain Age. Participants in an active control group (ACT) played the puzzle game Tetris. We measured brain activity during the training games using two channel NIRS before the intervention period. Cognitive functions were tested before and after the four-week intervention period. Results: The BT showed significant improvements in inhibition, processing speed, and working memory performance compared to ACT. The left and right DLPFC (dorsolateral prefrontal cortex) brain activities during the BT at baseline were associated with improvements in inhibition and processing speed. Discussion: This randomized control trial first provides scientific evidence that DLPFC activities during BT at baseline can predict cognitive improvements after a four-week intervention period.

本文言語English
論文番号560
ページ(範囲)1-15
ページ数15
ジャーナルBrain Sciences
10
8
DOI
出版ステータスPublished - 2020 8

ASJC Scopus subject areas

  • 神経科学(全般)

フィンガープリント

「Dorsolateral prefrontal cortex activity during a brain training game predicts cognitive improvements after four weeks’ brain training game intervention: Evidence from a randomized controlled trial」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル