Does the addition of cement improve the rate of local recurrence after curettage of giant cell tumours in bone?

C. L. Gaston, R. Bhumbra, M. Watanuki, A. T. Abudu, S. R. Carter, L. M. Jeys, R. M. Tillman, R. J. Grimer

研究成果: Article査読

66 被引用数 (Scopus)

抄録

We retrospectively compared the outcome after the treatment of giant cell tumours of bone either with curettage alone or with adjuvant cementation. Between 1975 and 2008, 330 patients with a giant cell tumour were treated primarily by intralesional curettage, with 84 (25%) receiving adjuvant bone cement in the cavity. The local recurrence rate for curettage alone was 29.7% (73 of 246) compared with 14.3% (12 of 84) for curettage and cementation (p = 0.001). On multivariate analysis both the stage of disease and use of cement were independent significant factors associated with local recurrence. The use of cement was associated with a higher risk of the subsequent need for joint replacement. In patients without local recurrence, 18.1% (13 of 72) of those with cement needed a subsequent joint replacement compared to 2.3% (4 of 173) of those without cement (p = 0.001). In patients who developed local recurrence, 75.0% (9 of 12) of those with previous cementation required a joint replacement, compared with 45.2% (33 of 73) of those without cement (p = 0.044).

本文言語English
ページ(範囲)1665-1669
ページ数5
ジャーナルJournal of Bone and Joint Surgery - Series B
93 B
12
DOI
出版ステータスPublished - 2011 12月

ASJC Scopus subject areas

  • 外科
  • 整形外科およびスポーツ医学

フィンガープリント

「Does the addition of cement improve the rate of local recurrence after curettage of giant cell tumours in bone?」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル