Distinctive flow pattern of wall shear stress and oscillatory shear index: Similarity and dissimilarity in ruptured and unruptured cerebral aneurysm blebs

Tomohiro Kawaguchi, Shinjitsu Nishimura, Masayuki Kanamori, Hiroki Takazawa, Shunsuke Omodaka, Kenya Sato, Noriko Maeda, Yoko Yokoyama, Hiroshi Midorikawa, Tatsuya Sasaki, Michiharu Nishijima

研究成果: Article査読

63 被引用数 (Scopus)

抄録

Object: The difference in the hemodynamics of wall shear stress (WSS) and oscillatory shear index (OSI) between ruptured and unruptured aneurysms is not well understood. The authors investigated the hemodynamic similarities and dissimilarities in ruptured and thin-walled unruptured aneurysm blebs. Methods: Magnetic resonance imaging-based fluid dynamics analysis was used to calculate WSS and OSI, and hemodynamic and intraoperative findings were compared. The authors also compared ruptured and unruptured thinwalled blebs for the magnitude of WSS and OSI. Results: Intraoperatively, 13 ruptured and 139 thin-walled unruptured aneurysm blebs were identified. Twelve of the ruptured (92.3%) and 124 of the unruptured blebs (89.2%) manifested low WSS and high OSI. The degree of WSS was significantly lower in ruptured (0.49 ± 0.12 Pa) than in unruptured (0.64 ± 0.15 Pa; p < 0.01) blebs. Conclusions: Ruptured and unruptured blebs shared a distinctive pattern of low WSS and high OSI. The degree of WSS at the rupture site was significantly lower than in the unruptured thin-walled blebs.

本文言語English
ページ(範囲)774-780
ページ数7
ジャーナルJournal of neurosurgery
117
4
DOI
出版ステータスPublished - 2012 10月 1

ASJC Scopus subject areas

  • 外科
  • 臨床神経学

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