Direct intestinal absorption of red fruit anthocyanins, cyanidin-3- glucoside and cyanidin-3,5-diglucoside, into rats and humans

Teruo Miyazawa, Kiyotaka Nakagawa, Miyuki Kudo, Kayo Muraishi, Keita Someya

研究成果: Article査読

346 被引用数 (Scopus)

抄録

We determined red fruit anthocyanins, cyanidin-3-glucoside (Cy-g) and cyanidin-3,5-diglucoside (Cy-dg), incorporated into plasma and liver of rats and human plasma by UV-HPLC. Fifteen minutes after an oral supplementation of a mixture of 320 mg of Cy-g and 40 mg of Cy-dg/kg of body weight, rats showed an increase to a maximum of 1563 μg (3490 nmol) of Cy-g/L and 195 μg (320 nmol) of Cy-dg/L in plasma and 0.067 μg (0.15 nmol) of Cy-g/g and a trace of Cy-dg together with methylated metabolites such as peonidin-3-glucoside in liver. In human plasma, 30 min after intake (2.7 mg of Cy-g and 0.25 mg of Cy-dg/kg of body weight), an average of 11 μg (24 nmol) of Cy-g/L and a trace of Cy-dg were found. Cyanidin as aglycone of Cy-g and Cy-dg was not found in such plasma samples, neither were conjugated and methylated anthocyanins. The results indicated that anthocyanins are incorporated keeping structurally intact glycoside forms, from the digestive tract into the blood circulation system in mammals.

本文言語English
ページ(範囲)1083-1091
ページ数9
ジャーナルJournal of Agricultural and Food Chemistry
47
3
DOI
出版ステータスPublished - 1999 3月 1

ASJC Scopus subject areas

  • 化学 (全般)
  • 農業および生物科学(全般)

フィンガープリント

「Direct intestinal absorption of red fruit anthocyanins, cyanidin-3- glucoside and cyanidin-3,5-diglucoside, into rats and humans」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル