Differential expression of Tbx4 and Tbx5 in Zebrafish Fin buds

Koji Tamura, Sayuri Yonei-Tamura, Juan Carlos Izpisúa Belmonte

研究成果: Article査読

55 被引用数 (Scopus)

抄録

In here we report the identification of two new members of the T-box gene family, zf-tbx5 and zf-tbx4, from the Zebrafish, Danio rerio. The amino acid sequences within the T-box domain share high homology with the mouse, chick, and newt orthologs. Whole mount in situ hybridization revealed specific expression of these genes in the eye and Fin buds. zf-tbx5 expression is restricted to the pectoral Fin bud, whilst zf-tbx4 transcripts are confined in the pelvic Fin bud. These results reveal the conserved expression pattern of Tbx5 and Tbx4 during appendage development in all animal species studied to date. Copyright (C) 1999 Elsevier Science Ireland Ltd.

本文言語English
ページ(範囲)181-184
ページ数4
ジャーナルMechanisms of Development
87
1-2
DOI
出版ステータスPublished - 1999 9 1
外部発表はい

ASJC Scopus subject areas

  • Embryology
  • Developmental Biology

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