Dietary administration of tetrodotoxin and its putative biosynthetic intermediates to the captive-reared non-toxic Japanese fire-bellied newt, Cynops pyrrhogaster

研究成果: Article査読

17 被引用数 (Scopus)

抄録

The origin of tetrodotoxin (TTX) in amphibians has long been disputed. In this study, TTX and its putative biosynthetic intermediates or shunt compounds (4,9-anhydro-10-hemiketal-5-deoxyTTX and Cep-242) were dietary administered to the captive-reared, non-toxic Japanese fire-bellied newt, Cynops pyrrhogaster. After 4 weeks, the ingested compounds were detected mainly in the newt body using liquid chromatography-mass spectrometry (LC-MS), while these compounds were not converted into other TTX analogues in newts.

本文言語English
ページ(範囲)78-82
ページ数5
ジャーナルToxicon
137
DOI
出版ステータスPublished - 2017 10月

ASJC Scopus subject areas

  • 毒物学

フィンガープリント

「Dietary administration of tetrodotoxin and its putative biosynthetic intermediates to the captive-reared non-toxic Japanese fire-bellied newt, Cynops pyrrhogaster」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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