Development of UV thermal lens microscope (UV-TLM) for ultrasensitive and direct detection of non-labeled biomolecules on a microchip

Manabu Tokeshi, Shinichiro Hiki, Kazuma Mawatari, Akihide Hibara, Takehiko Kitamori

研究成果: Conference contribution

抄録

This paper describes the development of an ultraviolet thermal lens microscope (UVTLM) that can detect directly non-labeled biomolecules in microchips. The performance of the UV-TLM was evaluated by the limit of detection (LOD) using standard solution of adenine. The LOD for adenine was calculated to be 1.4×10-8 M. This sensitivity was 100 times higher than that obtained by conventional spectrophotometry.

本文言語English
ホスト出版物のタイトルMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
ホスト出版物のサブタイトル9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Transducer Research Foundation
ページ452-454
ページ数3
ISBN(印刷版)0974361119, 9780974361116
出版ステータスPublished - 2005
外部発表はい
イベント9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
継続期間: 2005 10 92005 10 13

出版物シリーズ

名前Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
1

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
国/地域United States
CityBoston, MA
Period05/10/905/10/13

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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