TY - JOUR
T1 - Development of molecular imaging probes in oncology
AU - Iwata, Ren
PY - 2008/8
Y1 - 2008/8
N2 - Molecular imaging probes used for positron emission tomography(PET)in oncology are reviewed. Although [18F] FDG is presently the most useful probe for imaging tumors, there is a need for complementary probes of FDG with some limitations on detection in the brain or inflammatory region. The review is mostly focused on 18F-labeled probes designed for amino acid transport and protein synthesis, DNA synthesis, membrane lipid, and hypoxia such as FET, FLT, FMAU, fluorocholine, and FMISO, together with our original probes of FMT and FRP-170.
AB - Molecular imaging probes used for positron emission tomography(PET)in oncology are reviewed. Although [18F] FDG is presently the most useful probe for imaging tumors, there is a need for complementary probes of FDG with some limitations on detection in the brain or inflammatory region. The review is mostly focused on 18F-labeled probes designed for amino acid transport and protein synthesis, DNA synthesis, membrane lipid, and hypoxia such as FET, FLT, FMAU, fluorocholine, and FMISO, together with our original probes of FMT and FRP-170.
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M3 - Review article
C2 - 18701839
AN - SCOPUS:51449109331
SN - 0385-0684
VL - 35
SP - 1286
EP - 1290
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
IS - 8
ER -
