We developed a new solid biointerface by integrating a phospholipid polymer (PMBN) with a nanoscale surface modification process known as the electrospray deposition (ESD) method. In the enzyme immunoassay using this surface, the sensitivity was significantly enhanced. The surface prepared by ESD was nanosphere-shaped structure, therefore the highly uneven surface causes a drastic increase in specific signals due to an increase in the surface area. The PMBN surface which can conjugate antibodies prevented the nonspecific protein adsorption. The stability of the antibodies immobilized on the PMBN surface was improved drastically. The PMBN surface sprayed by ESD can be used to yield a highly sensitive, stable, and reliable assay.
|出版ステータス||Published - 2006|
|イベント||55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan|
継続期間: 2006 9 20 → 2006 9 22
|Other||55th Society of Polymer Science Japan Symposium on Macromolecules|
|Period||06/9/20 → 06/9/22|
ASJC Scopus subject areas