Development of an implantable small observation camera with scaffold chamber for angiogenesis

Y. Inoue, H. Nakagawa, I. Saito, T. Isoyama, H. Nakagawa, T. Ono, K. Ishii, E. Nakano, K. Imachi, Y. Abe

研究成果: Conference contribution

抄録

A miniaturized video camera system integrated with a scaffold for blood vessels and tissue induction that is implantable into an animal body was developed. A small autofocus camera with USB interface was used as an imaging device. A close-up lens was added to reduce the focusing point. Also 45-degree reflecting prism was added for the compact system design. A fabric poly-glycolic acid sheet of 0.3 mm thickness was used as a scaffold. The observation area was about 8 x 6 mm and the tissue was induced from sideways. The camera was implanted into a muscular layer of a goat for more than 9 weeks to observe the skeletal muscle induction. Tissue induction to the scaffold started from third week and it took about 9 weeks to cover the entire area by the tissue, Vigorous angiogenesis was observed at the front region of tissue induction resulting dense distribution of capillary vessels and red blood cells. The density of capillary vessels reduced considerably behind the front region and arterioles and venules started to appear.

本文言語English
ホスト出版物のタイトルWorld Congress on Medical Physics and Biomedical Engineering
ページ1961-1964
ページ数4
DOI
出版ステータスPublished - 2013
イベントWorld Congress on Medical Physics and Biomedical Engineering - Beijing, China
継続期間: 2012 5 262012 5 31

出版物シリーズ

名前IFMBE Proceedings
39 IFMBE
ISSN(印刷版)1680-0737

Other

OtherWorld Congress on Medical Physics and Biomedical Engineering
国/地域China
CityBeijing
Period12/5/2612/5/31

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 生体医工学

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