A 2D imaging system using closed bipolar electrodes (cBPEs) and electrochemiluminescence (ECL) is expected to realize high spatio-temporal resolution imaging. However, imaging of the distributions of molecules that cause an oxidation reaction on the electrode surface was not achieved by the cBPE/ECL system because the conventionally used luminophore can generate ECL only by an oxidation reaction. In this paper, we propose to implement a cathodic luminophore, [Ru(bpy)3]Cl2/glutathione disulfide (GSSG) producing ECL by reduction reaction into the cBPE/ECL system to enable detection and 2D imaging of dopamine, which is an oxidizable redox species and an important neurotransmitter. The applicability of [Ru(bpy)3]Cl2/GSSG for dopamine detection using a single cBPE was shown and its electrochemical properties were discussed. In addition, the demonstration of the 2D imaging of dopamine was performed using a cBPE array. These results show the potential to greatly expand the applicability of detection and imaging systems using cBPE/ECL.
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