Design of resolving reagents: p-substituted mandelic acids as resolving reagents for 1-arylalkylamines

Kazushi Kinbara, Kenichi Sakai, Yukihiko Hashimoto, Hiroyuki Nohira, Kazuhiko Saigo

研究成果: Article査読

59 被引用数 (Scopus)

抄録

The resolution of 1-arylalkylamines 2-10 by mandelic acid 1 was studied. It was found that a substituent, which elongated the molecular length of the amines, diminished the resolution efficiency. On the basis of these results, (S)-p-methylmandelic acid (S)-11 and (R)-p-methoxymandelic acid (R)-12 were selected as new resolving reagents for the 1-arylalkylamines; these acids were found to have a higher resolving ability than (R)-1.

本文言語English
ページ(範囲)1539-1542
ページ数4
ジャーナルTetrahedron Asymmetry
7
6
DOI
出版ステータスPublished - 1996 6

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

フィンガープリント 「Design of resolving reagents: p-substituted mandelic acids as resolving reagents for 1-arylalkylamines」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル