Design and function of amylose-poly(L-lysine) conjugate nanogels

Junko Tamada, Mio Yamazaki, Nobuyuki Morimoto, Longliang Wu, Kaoru Takada, Sung Won Choi, Atsushi Maruyama, Kazunari Akiyosh

研究成果: Paper査読

抄録

Poly(L-lysine) (PLL) can interact with DNA and forms stable polyion complex (PIC). Novel amylose primers those consist of maltopentaose (MP) and PLL or cholesteryl PLL were designed. 30% of MP substituted PLL (MaPLL, CH-MaPLL) were synthesized by reductive animation reaction. The MP-PLL and CH-MaPLL copolymers were enzymatically polymerized and the degree of polymerization (DP) was linearly increased in accordance to the polymerization time. Positive charge of the conjugates was shielded with increasing the degree of polymerization. Interaction of the conjugates with DNA was investigated.

本文言語English
ページ4808
ページ数1
出版ステータスPublished - 2006
外部発表はい
イベント55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
継続期間: 2006 9 202006 9 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period06/9/2006/9/22

ASJC Scopus subject areas

  • Engineering(all)

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