TY - JOUR
T1 - Dermatofibroma with diffuse eosinophilic infiltrate
AU - Aiba, Setsuya
AU - Terui, Tadashi
AU - Tagami, Hachiro
PY - 2000/6/1
Y1 - 2000/6/1
N2 - Dermatofibroma, a common form of benign fibrous histiocytoma, is characterized by the presence of different cell types consisting of fibroblastic, histiocytic, and even multinucleated cells. Dermatofibromas are always accompanied by an inflammatory lymphoid cell reaction, including B cells and T cells at their border. To our knowledge, however, there is no report of an infiltration of eosinophils within this tumor. We describe a dermatofibroma on the pretibial region of an 8-year-old boy. Microscopic examination revealed a diffuse eosinophilic infiltration within the dermatofibroma, which was typically composed of histiocytic cells and mature collagen. The diagnosis of dermatofibroma was confirmed by demonstrating the immunoreactivity of tumor cells to an anti-factor XIIIa antibody.
AB - Dermatofibroma, a common form of benign fibrous histiocytoma, is characterized by the presence of different cell types consisting of fibroblastic, histiocytic, and even multinucleated cells. Dermatofibromas are always accompanied by an inflammatory lymphoid cell reaction, including B cells and T cells at their border. To our knowledge, however, there is no report of an infiltration of eosinophils within this tumor. We describe a dermatofibroma on the pretibial region of an 8-year-old boy. Microscopic examination revealed a diffuse eosinophilic infiltration within the dermatofibroma, which was typically composed of histiocytic cells and mature collagen. The diagnosis of dermatofibroma was confirmed by demonstrating the immunoreactivity of tumor cells to an anti-factor XIIIa antibody.
KW - Dermal dendritic cells
KW - Dermatofibroma
KW - Eosinophilia
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U2 - 10.1097/00000372-200006000-00015
DO - 10.1097/00000372-200006000-00015
M3 - Article
C2 - 10871076
AN - SCOPUS:0034044409
VL - 22
SP - 281
EP - 284
JO - American Journal of Dermatopathology
JF - American Journal of Dermatopathology
SN - 0193-1091
IS - 3
ER -