Deregulation of sucrose-controlled translation of a bZIP-type transcription factor results in sucrose accumulation in leaves

Sunil Kumar Thalor, Thomas Berberich, Sung Shin Lee, Seung Hwan Yang, Xu Jun Zhu, Ryozo Imai, Yoshihiro Takahashi, Tomonobu Kusano

    研究成果: Article査読

    25 被引用数 (Scopus)

    抄録

    Sucrose is known to repress the translation of Arabidopsis thaliana AtbZIP11 transcript which encodes a protein belonging to the group of S (S - stands for small) basic region-leucine zipper (bZIP)-type transcription factor. This repression is called sucrose-induced repression of translation (SIRT). It is mediated through the sucrose-controlled upstream open reading frame (SC-uORF) found in the AtbZIP11 transcript. The SIRT is reported for 4 other genes belonging to the group of S bZIP in Arabidopsis. Tobacco tbz17 is phylogenetically closely related to AtbZIP11 and carries a putative SC-uORF in its 5′-leader region. Here we demonstrate that tbz17 exhibits SIRT mediated by its SC-uORF in a manner similar to genes belonging to the S bZIP group of the Arabidopsis genus. Furthermore, constitutive transgenic expression of tbz17 lacking its 5′-leader region containing the SC-uORF leads to production of tobacco plants with thicker leaves composed of enlarged cells with 3-4 times higher sucrose content compared to wild type plants. Our finding provides a novel strategy to generate plants with high sucrose content.

    本文言語English
    論文番号e33111
    ジャーナルPloS one
    7
    3
    DOI
    出版ステータスPublished - 2012 3 22

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)
    • Agricultural and Biological Sciences(all)
    • General

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