Growth of leptospiras in the presence of diphenylamine (DPA) caused a decrease in the content of leptospiral lipopolysaccharide (LPS). In association with this decrease of LPS, leptospiras became susceptible to anti-leptospiral action of normal rabbit serum (NRS), leptospiricidal action of antibody and complement, and killing by phagocytes. DPA-treated leptospiras were eliminated rapidly from the blood of infected mice and could not grow in the animals.
|ジャーナル||Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A|
|出版ステータス||Published - 1986|
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