Decreased lipopolysaccharide Content and Enhanced Susceptibility of Leptospiras to Serum Leptospiricidal Action and Phagocytosis After Treatment with Diphenylamine

Emiko Isogai, Hiroshi Isogai, Nobuyoshi Ito

研究成果: Article査読

4 被引用数 (Scopus)

抄録

Growth of leptospiras in the presence of diphenylamine (DPA) caused a decrease in the content of leptospiral lipopolysaccharide (LPS). In association with this decrease of LPS, leptospiras became susceptible to anti-leptospiral action of normal rabbit serum (NRS), leptospiricidal action of antibody and complement, and killing by phagocytes. DPA-treated leptospiras were eliminated rapidly from the blood of infected mice and could not grow in the animals.

本文言語English
ページ(範囲)438-447
ページ数10
ジャーナルZentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A
262
4
DOI
出版ステータスPublished - 1986
外部発表はい

ASJC Scopus subject areas

  • 免疫学

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