COXPRESdb in 2015: Coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems

研究成果: Article査読

103 被引用数 (Scopus)

抄録

The COXPRESdb (http://coxpresdb.jp) provides gene coexpression relationships for animal species. Here, we report the updates of the database, mainly focusing on the following two points. For the first point, we added RNAseq-based gene coexpression data for three species (human, mouse and fly), and largely increased the number of microarray experiments to nine species. The increase of the number of expression data with multiple platforms could enhance the reliability of coexpression data. For the second point, we refined the data assessment procedures, for each coexpressed gene list and for the total performance of a platform. The assessment of coexpressed gene list now uses more reasonable Pvalues derived from platform-specific null distribution. These developments greatly reduced pseudopredictions for directly associated genes, thus expanding the reliability of coexpression data to design new experiments and to discuss experimental results.

本文言語English
ページ(範囲)D82-D86
ジャーナルNucleic acids research
43
D1
DOI
出版ステータスPublished - 2015 1 28

ASJC Scopus subject areas

  • 遺伝学

フィンガープリント

「COXPRESdb in 2015: Coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル