Correlation between Reynolds number and eccentricity effect in stenosed artery models

Ashkan Javadzadegan, Yasutomo Shimizu, Masud Behnia, Makoto Ohta

研究成果: Article査読

14 被引用数 (Scopus)

抄録

BACKGROUND: Flow recirculation and shear strain are physiological processes within coronary arteries which are associated with pathogenic biological pathways. Distinct Quite apart from coronary stenosis severity, lesion eccentricity can cause flow recirculation and affect shear strain levels within human coronary arteries. OBJECTIVE: The aim of this study is to analyse the effect of lesion eccentricity on the transient flow behaviour in a model of a coronary artery and also to investigate the correlation between Reynolds number (Re) and the eccentricity effect on flow behaviour. METHODS: A transient particle image velocimetry (PIV) experiment was implemented in two silicone based models with 70% diameter stenosis, one with eccentric stenosis and one with concentric stenosis. RESULTS: At different times throughout the flow cycle, the eccentric model was always associated with a greater recirculation zone length, maximum shear strain rate and maximum axial velocity; however, the highest and lowest impacts of eccentricity were on the recirculation zone length and maximum shear strain rate, respectively. Analysis of the results revealed a negative correlation between the Reynolds number (Re) and the eccentricity effect on maximum axial velocity, maximum shear strain rate and recirculation zone length. CONCLUSIONS: As Re number increases the eccentricity effect on the flow behavior becomes negligible.

本文言語English
ページ(範囲)357-367
ページ数11
ジャーナルTechnology and Health Care
21
4
DOI
出版ステータスPublished - 2013

ASJC Scopus subject areas

  • 生物理学
  • バイオエンジニアリング
  • 情報システム
  • 生体材料
  • 生体医工学
  • 健康情報学

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