Copper-Catalyzed Coupling of 2-Siloxy-1-alkenes and Diazocarbonyl Compounds: Approach to Multisubstituted Furans, Pyrroles, and Thiophenes

Wei Wen Tan, Naohiko Yoshikai

研究成果: Article査読

24 被引用数 (Scopus)

抄録

We report herein copper(II)-catalyzed cyclization reactions of silyl enol ethers derived from methyl ketones with α-diazo-β-ketoesters or α-diazoketones to afford 2-siloxy-2,3-dihydrofuran derivatives or 2,3,5-trisubstituted furans, respectively, under mild conditions. The former cyclization products serve as versatile 1,4-diketone surrogates, allowing facile preparation of 2,3,5-trisubstituted furans, pyrroles, and thiophenes.

本文言語English
ページ(範囲)5566-5573
ページ数8
ジャーナルJournal of Organic Chemistry
81
13
DOI
出版ステータスPublished - 2016 7 1
外部発表はい

ASJC Scopus subject areas

  • 有機化学

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