TY - JOUR
T1 - Continuous low-dose ketamine improves the analgesic effects of fentanyl patient-controlled analgesia after cervical spine surgery
AU - Yamauchi, Masanori
AU - Asano, Makoto
AU - Watanabe, Masanori
AU - Iwasaki, Soushi
AU - Furuse, Shingo
AU - Namiki, Akiyoshi
PY - 2008/9
Y1 - 2008/9
N2 - BACKGROUND:: The effects of fentanyl with ketamine for postoperative pain are unknown. We investigated the adjuvant effects of ketamine for fentanyl patient-controlled analgesia. METHODS:: Cervical and lumbar spine surgery patients were divided into three groups: ketamine 1 mg/kg followed by 42 and 83 μg • kg • h in ketamine-1 and ketamine-2 group, respectively, and a control group. Postoperative patient-controlled analgesia fentanyl was administered with a background infusion. RESULTS:: Pain scores and analgesia requirement in the ketamine-2 group were significantly lower than those of the control group after cervical surgery. Ketamine partially improved the analgesic effects of fentanyl after lumbar surgery. CONCLUSION:: Small-dose ketamine improved the analgesic effects of fentanyl after cervical surgery.
AB - BACKGROUND:: The effects of fentanyl with ketamine for postoperative pain are unknown. We investigated the adjuvant effects of ketamine for fentanyl patient-controlled analgesia. METHODS:: Cervical and lumbar spine surgery patients were divided into three groups: ketamine 1 mg/kg followed by 42 and 83 μg • kg • h in ketamine-1 and ketamine-2 group, respectively, and a control group. Postoperative patient-controlled analgesia fentanyl was administered with a background infusion. RESULTS:: Pain scores and analgesia requirement in the ketamine-2 group were significantly lower than those of the control group after cervical surgery. Ketamine partially improved the analgesic effects of fentanyl after lumbar surgery. CONCLUSION:: Small-dose ketamine improved the analgesic effects of fentanyl after cervical surgery.
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U2 - 10.1213/ane.0b013e31817f1e4a
DO - 10.1213/ane.0b013e31817f1e4a
M3 - Article
C2 - 18713926
AN - SCOPUS:51449117404
VL - 107
SP - 1041
EP - 1044
JO - Anesthesia and Analgesia
JF - Anesthesia and Analgesia
SN - 0003-2999
IS - 3
ER -