Continuous low-dose ketamine improves the analgesic effects of fentanyl patient-controlled analgesia after cervical spine surgery

Masanori Yamauchi, Makoto Asano, Masanori Watanabe, Soushi Iwasaki, Shingo Furuse, Akiyoshi Namiki

研究成果: Article査読

41 被引用数 (Scopus)

抄録

BACKGROUND:: The effects of fentanyl with ketamine for postoperative pain are unknown. We investigated the adjuvant effects of ketamine for fentanyl patient-controlled analgesia. METHODS:: Cervical and lumbar spine surgery patients were divided into three groups: ketamine 1 mg/kg followed by 42 and 83 μg • kg • h in ketamine-1 and ketamine-2 group, respectively, and a control group. Postoperative patient-controlled analgesia fentanyl was administered with a background infusion. RESULTS:: Pain scores and analgesia requirement in the ketamine-2 group were significantly lower than those of the control group after cervical surgery. Ketamine partially improved the analgesic effects of fentanyl after lumbar surgery. CONCLUSION:: Small-dose ketamine improved the analgesic effects of fentanyl after cervical surgery.

本文言語English
ページ(範囲)1041-1044
ページ数4
ジャーナルAnesthesia and Analgesia
107
3
DOI
出版ステータスPublished - 2008 9
外部発表はい

ASJC Scopus subject areas

  • 麻酔学および疼痛医療

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