Construction of fluorinated chiral center

研究成果: Review article査読

抄録

Fluorinated compounds have drawn the attention of medicinal chemists because of their potential metabolic tolerance and modulation of drug efficacy. Thus stereo- and enantioselective construction of fluorinated carbon center is an important issue. In spite of remarkable progress in the last decade, the first effective method of catalytic enantioselective fluorination by nucleophilic fluorine reagent has been reported in this year. In this article, construction of fluorinated chiral center is reviewed being categolized into three classes.

本文言語English
ページ(範囲)962-963
ページ数2
ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
68
9
DOI
出版ステータスPublished - 2010 9
外部発表はい

ASJC Scopus subject areas

  • 有機化学

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