Condensed Heteroaromatic Ring Systems. III.1,2) Synthesis of Naphthyridine Derivatives by Cyclization of Ethynylpyridinecarboxamides

Takao Sakamoto, Yoshinori Kondo, Hiroshi Yamanaka

研究成果: Article査読

51 被引用数 (Scopus)

抄録

Four kinds of naphthyridinones, i.e. l,6-naphthyridin-5-one, l,7-naphthyridin-8-one, 2,6-naphthyridin-2-one, and 2,7-naphthyridin-l-one derivatives, were commonly synthesized by the intramolecular cyclization of pyridinecarboxamides having an ethynyl group or β,β-dimethoxyethyl group adjacent to the carbamoyl group. The syntheses of the starting pyridine derivatives were easily accomplished by cross-coupling of the corresponding halopyridines with acetylenes.

本文言語English
ページ(範囲)626-633
ページ数8
ジャーナルChemical and Pharmaceutical Bulletin
33
2
DOI
出版ステータスPublished - 1985

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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