Computational simulation of blood flow dynamics using an anatomically realistic artery model constructed from medical images

Yuji Shimogonya, Kazuhiro Itoh, Hiroshige Kumamaru

研究成果: Conference contribution

抄録

Hemodynamics is believed to play a vital role in the initiation of cerebral aneurysms. In this study, we describe a newly defined hemodynamic quantity, the gradient oscillatory number (GON), as an index for the cerebral aneurysm initiation. It is defined by temporal variations of flow-induced tension/compression forces acting on endothelial cells. We calculated the index for the arterial geometry before aneurysm formation, which was constructed by artificially removing the aneurysm from a medical image-based arterial geometry. The result showed that the index had a strong correlation with the location of aneurysm formation. This suggests that the proposed index, GON, may be useful as a hemodynamic index for the initiation of cerebral aneurysms.

本文言語English
ホスト出版物のタイトル2010 World Automation Congress, WAC 2010
出版ステータスPublished - 2010 12 1
イベント2010 World Automation Congress, WAC 2010 - Kobe, Japan
継続期間: 2010 9 192010 9 23

出版物シリーズ

名前2010 World Automation Congress, WAC 2010

Other

Other2010 World Automation Congress, WAC 2010
CountryJapan
CityKobe
Period10/9/1910/9/23

ASJC Scopus subject areas

  • Control and Systems Engineering

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